גנטיקה קלינית

TRISONOMIES: 13,18, 21
TRISOMIA 21  – SYNDROM OF DOWN
. This result from meiotic nondisjunction of the chromosome 21 pair
The risk to have a child with Down´s syndrome increase with maternal age, specially after the age of 30 years as result from meiotic non-disjunction of the chromosome  21 pair
cause
4% Its heritange
it s posible to identify  with karyotype
Most of the case its for Division Non-Disjunction